Volume 5, 1820 June 23–1821 February 19

Subjects include routine business letters, the Lucy Backus Woodbridge estate, family correspondence, resignation of William Woodbridge from Congress, rental of Blennerhassett Island. Business firms mentioned: Benjamin J. Gilman, W. Wilson & Co., Robert Fulton, R. J. Meigs, Clarissa Backus, J. W. Biddle & Co., and John Sproule. Places of business include: Philadelphia, Pittsburgh, Frankfort, Lexington, Washington D.C., Zanesville, Chillicothe, Detroit, Clarksburg, and Parkersburg.